A case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT

Table 1 Previous Case Reports of Head and Neck Cutaneous Ischemia Secondary to CAD

Authors	Involved Region(s)	Treatment Regimen	Outcome
Poldre and collagues (1985) [4]	Nasal tip, toes, fingers	Plasmapheresis, sulfinpyrazone, dipyridamole, prednisone	Loss of 8 toes, no comment regarding outcome of nasal tip ischemia
Oh and colleagues (2009) [5]	Cheek, thigh	ASA (100 mg/day), supportive wound care	Partial resolution, with some necrosis leading to permanent scarring
Jeskowiak & George (2013) [6]	Ear	Heparin, isoprost, plasmapheresis and surgical debridement	Initial improvement, subsequently lost to follow up
Mishra & colleagues (2013) [7]	Cheeks, nasal tip, ears, hands and buttocks	Full text not available for this paper

ISSN: 1916-0216