The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study

Table 2 Relationships between alleles of IL-1 receptor genetic polymorphisms and age-related hearing impairment

Gene	SNPs	Allele	ARHI	Control	Crude		Adjusted^a
Gene	SNPs	Allele	ARHI	Control	OR (95% CI)	P	OR (95% CI)	p
IL1R1	rs3917225	A	216 (63.2%)	186 (57.1%)	1.000		1.000
		G	126 (36.8%)	140 ((42.9%)	0.775 (0.568–1.057)	0.107	0.587 (0.383–0.901)	0.015*
	rs2234650	C	270 (75.4%)	225 (71.7%)	1.000		1.000
		T	88 (24.6%)	89 (28.3%)	0.934 (0.664–1.313)	0.694	1.028 (0.654–1.616)	0.905
IL1R2	rs4141134	T	343 (96.3%)	333 (96.2%)	1.000		1.000
		C	13 (3.7%)	13 (3.8%)	0.971 (0.444–2.125)	0.941	0.595 (0.209–1.699)	0.332
	rs2071008	G	276 (78.4%)	261 (79.6%)	1.000		1.000
		T	76 (21.6%)	67 (20.4%)	1.073 (0.741–1.552)	0.710	1.062 (0.641–1.760)	0.816

ISSN: 1916-0216