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Table 2 Relationships between alleles of HSP70 genetic polymorphisms and age-related hearing impairment

From: The association of heat shock protein genetic polymorphisms with age-related hearing impairment in Taiwan

Gene SNP Allele ARHI Control Crude Adjusteda
OR (95% CI) p OR (95% CI) p
HSPA1A rs1043618 G 202 (71.1%) 209 (73.1%) 1.000   1.000  
   C 82 (28.9%) 77 (26.9%) 1.102 (0.764–1.589) 0.604 1.111 (0.763–1.618) 0.583
HSPA1L rs2227956 A 227 (79.4%) 241 (83.1%) 1.000   1.000  
   G 59 (20.6%) 49 (16.9%) 1.278 (0.840–1.946) 0.252 1.333 (0.863–2.508) 0.195
  rs2075800 C 176 (60.7%) 181 (62.8%) 1.000   1.000  
   T 114 (39.3%) 107 (37.2%) 1.096 (0.783–1.533) 0.594 1.033 (0.730–1.461) 0.854
HSPA1B rs2763979 C 214 (74.8%) 171 (60.6%) 1.000   1.000  
   T 72 (25.2%) 112 (39.4%) 0.517 (0.361–0.739) < 0.001** 0.520 (0.360–0.751) < 0.001**
  1. a: adjusted for sex and noise exposure
  2. **: p < 0.001
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Journal of Otolaryngology - Head & Neck Surgery

ISSN: 1916-0216

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